Zinc L Carnosine Prevents Intestinal Damage, Pain, Inflammation of Strong Arthritis Meds (Indocin, Indomethacin)

Topics: Aging and Costs of Aging, Vitamins and Supplements, Wellness and Health

…and, good news for meat eaters.

Zinc-Carnosine is found in meat not plants, and in dietary supplements. It is stored in our muscles and in the brain.

When given to 10 people with 150 milligrams of indomethacin (a powerful prescription dose), 37.5mg of zinc carnosine twice daily stabilized the lining of the small intestine and prevented the intestine from being penetrated by the indomethacin.

Protecting the intestine usually means less inflammation and less bleeding, and less pain.

Zinc-carnosine has been reported to reduce GI side effects in people being treated for Hepatitis C. and has a long history of use as complementary therapy.

In Japan, Zinc Carnosine is available only by prescription, and is approved for gastric ulcers.

It improved the cure rate for H. Pylori stomach ulcers from 86 percent to 100 percent in 66 consecutive patients.

In animals, carnosine prevents rusting of fats in cell membranes, and blocks toxins that are created. This may be how carnosine reduces damage from arthritis medication indomethacin.

Other scientists have considered zinc carnosine as an anti-ulcer drug and therapy for inflammatory bowel syndrome.

They believe it activates nf-kb, which
a naturally protective anti-inflammatory protein.

Rich food sources of Zinc-l-carnosine“> are lean meats, such as red meats that end in -loin, such as sirloin and tenderloin, and buffalo, elk and other game meats.

Poultry and fish also contain carnosine: a serving of 4 ounces of animal protein offers between 50 and 250mg of carnosine, depending on the meat, though absorption is variable.

If you have to take strong arthritis meds, you shouldn’t have to have the side effects. Zinc-carnosine supplements may help.

  • Goat

    It was my understanding that zinc-l-carnosine was synthesized in Japan in a laboratory and that it does not exist naturally in that form in foods. Can you please clarify this for me? Thanks

  • That’s some of my understanding too: carnosine (also known as L carnosine) is a naturally occurring dipeptide (comprising β‐alanine and l‐histidine) which is an anti-oxidant, antiglycator and scavenger of zinc and copper ions that is likely to suppress oxidative stress. So zinc carnosine occurs as part of reactions in the body, though probably transiently.

    Zinc carnosine (ZnC) as a supplement is apparently “an artificially produced derivative of carnosine, where zinc and carnosine are linked in a one‐to‐one ratio to provide a polymeric structure.”

  • Leo Marcell

    You are right. The compound was created in Japan in 1983 by combining zinc and carnosine. The author makes it sound as if it is a naturally occurring compound that one can get through diet. The concentrations of zinc/carnosine are carefully measured to achieve a 1:1 ratio. All the studies done have use these ‘standardized compound’ and not food which is unlikely to achieve the results of the study. In other words, get the supplement and don’t experiment with diet as it is hard to duplicate the exact doses used in the scientific studies.